Ingredient Feature: Kinetin and Zeatin

02.24.2014, 10:53 CST | Posted In: Skin Care

Kinetin and Zeatin graphic

Nature’s inherent processes have been a fascination for centuries for those in medicine – we study sharks for answers to cancer, plants for remedies to pain, we even use eggs to culture everything from vaccines to cosmetic facial injectables – the list goes on and on.

Plant-based growth factors provide another example of recent fascination.  These cytokinins, as they are also called, have been incorporated into topical skincare.

Two powerful types of cytokinins are Kinetin and Zeatin. Both Kinetin and Zeatin have been shown to be effective in improving the appearance of aging skin and are the key ingredients in one of Obagi’s newest product lines designed for those with sensitive skin, the Gentle Rejuvenation System

When researching the plant DNA-derived ingredient Kinetin, scientists discovered that this plant-based growth factor prevented plant leaves from drying out and withering.  Soon, they realized the potential benefits Kinetin could have in skin care; they discovered that when used topically, Kinetin gently, yet effectively helps keep skin looking smooth and radiant.1 In as early as 6 weeks, Kinetin has been shown to diminish the appearance of spots by an average of 60%2 and in 24 weeks patients saw a 26% increase in skin’s ability to retain moisture3

Zeatin is RNA-derived from immature corn kernels and occurs naturally in plants. When used in skin care, Zeatin has been shown to improve skin appearance including roughness, fine lines and wrinkles, and reduce blotchiness after just 12 weeks4.

To discover how Kinetin and Zeatin could help to improve your sensitive skin, ask your skin care physician about the Gentle Rejuvenation System


1. What is Kinetin? (Accessed December 16, 2013) 2. Katz BE, Bruck MC. Efficacy and tolerability of kinetin 0.1% cream for improving the signs of photoaging in facial and neck skin. Cosmet Dermatol. 2006;19(12):736-741. 3. McCullough JL, Weinstein GD. Clinical study of safety and efficacy of using topical kinetin 0.1% (Kinerase®) to treat photodamaged skin. Cosmet Dermatol. 2002;15(9):29-32. 4. Cruz Jr PD, Reece BT. A clinical study of topical zeatin (0.10%, 0.025%) for improving the appearance of photodamaged skin (RCTS study #1837). 12-week final analysis, September 2005. OMP, Inc. Data on file.

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