Obagi-C® Rx System

Address early signs of skin aging and skin damage with
a unique regimen that combines the benefits of both
prescription-strength hydroquinone and Vitamin C.


Remarkable Results

See how the Obagi-C Rx System improved the appearance of hyperpigmentation (brown spots) and restored balance and clarity to lackluster skin in just 6 weeks.1

Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After
Obagi-C Rx Before & After

Photos have not been retouched. Results may vary.

In a clinical trial composed of subjects of varying ages and skin types, the Obagi-C Rx System for Normal to Oily Skin showed visible results in only 6 weeks when applied as directed.1

Clinically Proven Ingredients

Prescription-strength 4% Hydroquinone
  • Improves the appearance of hyperpigmentation (brown spots)
  • Restores balance, radiance, and clarity

View Important Safety Information and Full Prescribing Information for C-Clarifying Serum and C-Therapy Night Cream.

Vitamin C — 10% L-Ascorbic acid
  • Supports skin rejuvenation from the inside out
  • Lower pH formulation optimizes absorption
Deep Skin Penetration

When compared to SkinCeuticals Phloretin CF®, another leading Vitamin C product, the Obagi-C Rx C-Clarifying Serum delivered more Vitamin C into the skin and remained in the skin longer.*2

*Based on in vitro studies. Clinical significance has not been established.


Obagi-C Rx Delivers Powerful Results3,†

Week 12 Physician Assessment graph

Don’t just take our word for it. Read testimonials of real women who love the Obagi-C Rx System.

References: 1. Bruce S, Investigator. A single-center study to evaluate the efficacy of the Obagi-C® Rx System for Normal to Oily Skin in the treatment of minimal or mild photodamage and hyperpigmentation of the face in subjects with normal to oily skin. 6-week interim analysis. Data on file. 2. Lehman PA, Investigator, Cetero Research. Evaluation of the percutaneous absorption of 14C-ascorbic acid, in vitro, using the Franz human skin finite dose model (protocol R09-0715). Data on file. 3. Bruce S, Watson J. Evaluation of a prescription strength hydroquinone/L-ascorbic acid treatment system for normal to oily skin. Poster 802. OMP, Inc. Data on file.

Important Safety Information for C-Clarifying Serum and C-Therapy Night Cream

People with prior history of sensitivity or allergic reaction to this product or any of its ingredients should not use it. The safety of topical hydroquinone use during pregnancy or in children (12 years and under) has not been established.

Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes, nose, mouth, or lips with water and contact physician.

Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.

Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

Treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation, which does not preclude treatment.

Pregnancy Category C: Animal reproduction studies have not been conducted with topical hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically. Topical hydroquinone should be used on pregnant women only when clearly indicated.

Nursing Mothers: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother.

Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.

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